IL7R
interleukin 7 receptor
Synonyms:
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
Species:
Human IL7R (3575), Mouse Il7r (16197), Rat Il7r (294797), sheep IL7R (101111126), Domestic Rabbit IL7R (100343726), domestic guinea pig Il7r (100714027), naked mole-rat Il7r (101710077), Zebrafish il7r (100134973), dog IL7R (612582), domestic cat IL7R (101100697) ...More
UniProtKB ID:
Gene ID:
- Human(3575) Summary: The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008]
- Mouse(16197) interleukin 7 receptor
- Rat(294797) interleukin 7 receptor
- sheep(101111126) interleukin 7 receptor
- Domestic Rabbit(100343726) interleukin 7 receptor
- domestic guinea pig(100714027) interleukin 7 receptor
- naked mole-rat(101710077) interleukin 7 receptor
- Zebrafish(100134973) interleukin 7 receptor
- dog(612582) interleukin 7 receptor
- domestic cat(101100697) interleukin 7 receptor
- Horse(100034169) interleukin 7 receptor
- cow(521554) interleukin 7 receptor
- chicken(426054) interleukin 7 receptor
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Interleukin-7 Receptor α/CD127 antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
mouse
Application
flow cytometry
western blot
western blot
Anti-IL7R antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
western blot
western blot