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Merck

IL37

interleukin 37

Synonyms:
FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H, IL-1H4, IL-1RP1, IL-37, IL1F7, IL1H4, IL1RP1
Species:
Human IL37 (27178), cow IL37 (786493), dog IL37 (100686057), domestic guinea pig Il37 (101788929), naked mole-rat Il37 (101724994), sheep IL37 (101111617)
UniProtKB ID:
Q9NZH6, B5BU97, Q56AP9, Q8TD04, Q8TD05, Q9HBF2, Q9HBF3, Q9UHA6
Gene ID:
  • Human(27178) Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • cow(786493) interleukin 37
  • dog(100686057) interleukin 37
  • domestic guinea pig(101788929) interleukin 37
  • naked mole-rat(101724994) interleukin 37
  • sheep(101111617) interleukin 37

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB3500952
Anti-IL-37 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot