IGSF8
immunoglobulin superfamily, member 8
Synonyms:
CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL
Species:
Human IGSF8 (93185), Mouse Igsf8 (140559), Rat Igsf8 (304979), domestic guinea pig Igsf8 (100721506), naked mole-rat Igsf8 (101721418), sheep IGSF8 (101102283), Domestic Rabbit IGSF8 (100338663), Horse IGSF8 (100058209), cow IGSF8 (519266), dog IGSF8 (100855523)
UniProtKB ID:
Gene ID:
- Human(93185) Summary: This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
- Mouse(140559) immunoglobulin superfamily, member 8
- Rat(304979) immunoglobulin superfamily, member 8
- domestic guinea pig(100721506) immunoglobulin superfamily, member 8
- naked mole-rat(101721418) immunoglobulin superfamily, member 8
- sheep(101102283) immunoglobulin superfamily, member 8
- Domestic Rabbit(100338663) immunoglobulin superfamily, member 8
- Horse(100058209) immunoglobulin superfamily, member 8
- cow(519266) immunoglobulin superfamily, member 8
- dog(100855523) immunoglobulin superfamily, member 8
- domestic cat(101097041) immunoglobulin superfamily, member 8
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