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GPX1

glutathione peroxidase 1

Synonyms:
GPXD, GSHPX1
Species:
UniProtKB ID:
Gene ID:
  • Human(2876) Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14775) glutathione peroxidase 1
  • Rat(24404) glutathione peroxidase 1
  • Thale Cress(817046) phospholipid hydroperoxide glutathione peroxidase 1
  • chicken(100857115) glutathione peroxidase 1
  • domestic cat(101083751) glutathione peroxidase 1
  • cow(281209) glutathione peroxidase 1
  • Horse(100053396) glutathione peroxidase 1
  • dog(442961) glutathione peroxidase 1
  • sheep(100820742) glutathione peroxidase 1
  • Domestic Rabbit(100009258) glutathione peroxidase 1
  • domestic guinea pig(100729115) glutathione peroxidase 1
  • naked mole-rat(101710466) glutathione peroxidase 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Glutathione peroxidase 1 (ISO1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, pig
Application
ELISA
immunohistochemistry

western blot
ANTI-GPX1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-Gpx1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, mouse, rat
Application
ELISA
western blot
Anti-GPX1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
alligator, human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
GPX1 human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Species
human