GAD1
glutamate decarboxylase 1 (brain, 67kDa)
Synonyms:
CPSQ1, GAD, SCP
Species:
Human GAD1 (2571), Mouse Gad1 (14415), Rat Gad1 (24379), fruit fly Gad1 (38484), cow GAD1 (517552), domestic cat GAD1 (493699), dog GAD1 (478794), chicken GAD1 (395743), domestic guinea pig Gad1 (100271904), naked mole-rat Gad1 (101725846)
UniProtKB ID:
Gene ID:
- Human(2571) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
- Mouse(14415) glutamate decarboxylase 1
- Rat(24379) glutamate decarboxylase 1
- fruit fly(38484) Glutamic acid decarboxylase 1
- cow(517552) glutamate decarboxylase 1 (brain, 67kDa)
- domestic cat(493699) glutamate decarboxylase 1 (brain, 67kDa)
- dog(478794) glutamate decarboxylase 1 (brain, 67kDa)
- chicken(395743) glutamate decarboxylase 1 (brain, 67kDa)
- domestic guinea pig(100271904) glutamate decarboxylase 1
- naked mole-rat(101725846) glutamate decarboxylase 1 (brain, 67kDa)
- sheep(101117393) glutamate decarboxylase 1 (brain, 67kDa)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GAD1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GAD1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-GAD1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2919, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-GAD1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2914, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-GAD1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2911, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot