FBLN5
fibulin 5
Synonyms:
ADCL2, ARCL1A, ARMD3, DANCE, EVEC, FIBL-5, UP50
Species:
Human FBLN5 (10516), Mouse Fbln5 (23876), Rat Fbln5 (29158), sheep FBLN5 (101112927), Domestic Rabbit FBLN5 (100347343), domestic guinea pig Fbln5 (100715192), naked mole-rat Fbln5 (101709553), Zebrafish fbln5 (449806), cow FBLN5 (535185), Horse FBLN5 (100063331) ...More
UniProtKB ID:
Gene ID:
- Human(10516) Summary: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]
- Mouse(23876) fibulin 5
- Rat(29158) fibulin 5
- sheep(101112927) fibulin 5
- Domestic Rabbit(100347343) fibulin 5
- domestic guinea pig(100715192) fibulin 5
- naked mole-rat(101709553) fibulin 5
- Zebrafish(449806) fibulin 5
- cow(535185) fibulin 5
- Horse(100063331) fibulin 5
- domestic cat(101096324) fibulin 5
- dog(480227) fibulin 5
- chicken(423413) fibulin 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Fibulin 5/FBLN5 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
western blot
Monoclonal Anti-FBLN5 antibody produced in mouse, clone 1G6A4, ascites fluid,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
