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Merck

F11R

F11 receptor

Synonyms:
CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
Species:
UniProtKB ID:
Gene ID:
  • Human(50848) Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
  • Mouse(16456) F11 receptor
  • Rat(116479) F11 receptor
  • Zebrafish(323696) F11 receptor
  • dog(478974) F11 receptor
  • cow(281258) F11 receptor
  • domestic cat(653015) F11 receptor
  • chicken(100036512) F11 receptor
  • sheep(780487) F11 receptor
  • naked mole-rat(101713536) F11 receptor
  • domestic guinea pig(100733207) F11 receptor

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-F11R antibody produced in mouse, clone 2E3-1C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

proximity ligation assay

western blot
Anti-JAM-A antibody, Mouse monoclonal, clone J10.4, purified from hybridoma cell culture,
Species Reactivity
human
Application
western blot