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Merck

DNASE2B

deoxyribonuclease II beta

Synonyms:
DLAD
Species:
UniProtKB ID:
Gene ID:
  • Human(58511) Summary: The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(56629) deoxyribonuclease II beta
  • Rat(59296) deoxyribonuclease II beta
  • sheep(101110100) deoxyribonuclease II beta
  • domestic guinea pig(100732795) deoxyribonuclease II beta
  • naked mole-rat(101719320) deoxyribonuclease II beta
  • chicken(424540) deoxyribonuclease II beta
  • domestic cat(101097005) deoxyribonuclease II beta
  • cow(525117) deoxyribonuclease II beta
  • Horse(100064895) deoxyribonuclease II beta
  • dog(479973) deoxyribonuclease II beta

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