DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
Synonyms:
AADC
Species:
Human DDC (1644), Mouse Ddc (13195), Rat Ddc (24311), domestic guinea pig Ddc (100135516), naked mole-rat Ddc (101697555), sheep DDC (101106765), Zebrafish ddc (406651), chicken DDC (420947), fruit fly Ddc (35190), dog DDC (606852) ...More
UniProtKB ID:
Gene ID:
- Human(1644) Summary: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
- Mouse(13195) dopa decarboxylase
- Rat(24311) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- domestic guinea pig(100135516) dopa decarboxylase
- naked mole-rat(101697555) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- sheep(101106765) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- Zebrafish(406651) dopa decarboxylase
- chicken(420947) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- fruit fly(35190) Dopa decarboxylase
- dog(606852) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- cow(280762) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- Horse(100052557) dopa decarboxylase (aromatic L-amino acid decarboxylase)
- domestic cat(101082989) dopa decarboxylase (aromatic L-amino acid decarboxylase)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DDC antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rat
Application
western blot
Monoclonal Anti-DDC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2962, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-DOPA Decarboxylase (DDC) antibody produced in mouse, clone DDC-109, ascites fluid,
Species Reactivity
bovine, canine, guinea pig, human, monkey, rabbit, rat, sheep
Application
ELISA
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Benserazide for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human