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Merck

CST6

cystatin E/M

Synonyms:
Species:
Human CST6 (1474), Mouse Cst6 (73720), Rat Cst6 (171096), domestic guinea pig Cst6 (100712638), naked mole-rat Cst6 (101704358), sheep CST6 (101112685), dog CST6 (483719), domestic cat CST6 (101098336), cow CST6 (503685)
UniProtKB ID:
Q15828, Q540N7
Gene ID:
  • Human(1474) Summary: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype. [provided by RefSeq, Jul 2008]
  • Mouse(73720) cystatin E/M
  • Rat(171096) cystatin E/M
  • domestic guinea pig(100712638) cystatin E/M
  • naked mole-rat(101704358) cystatin E/M
  • sheep(101112685) cystatin E/M
  • dog(483719) cystatin E/M
  • domestic cat(101098336) cystatin E/M
  • cow(503685) cystatin E/M

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2107027
Anti-CST6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
WH0001474M1
Monoclonal Anti-CST6 antibody produced in mouse, clone 2H8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot