CRYM
crystallin, mu
Synonyms:
DFNA40, THBP
Species:
Human CRYM (1428), Mouse Crym (12971), Rat Crym (117024), Goat CRYM (100861024), sheep CRYM (101102280), naked mole-rat Crym (101706899), domestic guinea pig Crym (100717691), Zebrafish crym (791205), dog CRYM (479818), cow CRYM (505167) ...More
UniProtKB ID:
Gene ID:
- Human(1428) Summary: Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]
- Mouse(12971) crystallin, mu
- Rat(117024) crystallin, mu
- Goat(100861024) crystallin, mu
- sheep(101102280) crystallin, mu
- naked mole-rat(101706899) crystallin, mu
- domestic guinea pig(100717691) crystallin, mu
- Zebrafish(791205) crystallin, mu
- dog(479818) crystallin, mu
- cow(505167) crystallin, mu
- domestic cat(101080756) crystallin, mu
- chicken(427008) crystallin, mu
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