CDH1
cadherin 1, type 1, E-cadherin (epithelial)
Synonyms:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Species:
Human CDH1 (999), Mouse Cdh1 (12550), Rat Cdh1 (83502), Zebrafish cdh1 (114424), cow CDH1 (282637), domestic cat CDH1 (101095391), dog CDH1 (442858), chicken CDH1 (415860), domestic guinea pig Cdh1 (100726210), naked mole-rat Cdh1 (101719565) ...More
UniProtKB ID:
Gene ID:
- Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
- Mouse(12550) cadherin 1
- Rat(83502) cadherin 1
- Zebrafish(114424) cadherin 1, epithelial
- cow(282637) cadherin 1, type 1, E-cadherin (epithelial)
- domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
- dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
- chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
- domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
- naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
- sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
- sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CDH1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-CDH1 antibody produced in mouse, clone 67A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Cdh1 (Ab-2) Mouse mAb (DH01), liquid, clone DH01, Calbiochem®,
Species Reactivity
human
Application
Anti-Cdh1 antibody,Mouse monoclonal, clone DCS-266, purified from hybridoma cell culture,
Species Reactivity
human
Application
immunoprecipitation (IP)
microarray
western blot
microarray
western blot
Proteins
Product Number
Description
Species
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
mouse
E-Cadherin/ECAD/Cadherin-1/CD324 Protein human, recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE),
Species
human