CD8A
CD8a molecule
Synonyms:
CD8, Leu2, MAL, p32
Species:
Human CD8A (925), Mouse Cd8a (12525), Rat Cd8a (24930), Zebrafish cd8a (677754), chicken CD8A (428800), cow CD8A (281060), domestic cat CD8A (493799), dog CD8A (403157), chicken CD8A (403158), naked mole-rat Cd8a (101720748) ...More
UniProtKB ID:
Gene ID:
- Human(925) Summary: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
- Mouse(12525) CD8 antigen, alpha chain
- Rat(24930) CD8a molecule
- Zebrafish(677754) CD8 antigen, alpha polypeptide
- chicken(428800) CD8a molecule
- cow(281060) CD8a molecule
- domestic cat(493799) CD8a molecule
- dog(403157) CD8a molecule
- chicken(403158) CD8a molecule
- naked mole-rat(101720748) CD8a molecule
- domestic guinea pig(100379570) CD8 antigen, alpha chain
- sheep(101103464) CD8a molecule
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CD8 antibody, Rabbit monoclonal, clone SP16, recombinant, expressed in proprietary host, tissue culture supernatant,
Species Reactivity
human
Application
immunohistochemistry
Anti-CD8 antibody, Rabbit monoclonal, clone SP239, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
human, rat
Application
immunohistochemistry
Monoclonal Anti-CD8a antibody produced in mouse, clone OX-8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
rat
Application
FUNC
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
Monoclonal Anti-CD8 antibody produced in mouse, clone UCHT-4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Anti-Human CD8a (RPA-T8) ColorWheel® Dye-Ready mAb, for use with ColorWheel® Dyes (Required, sold separately),
Species Reactivity
human, nonhuman primates
Application
flow cytometry