CD207
CD207 molecule, langerin
Synonyms:
CLEC4K
Species:
Human CD207 (50489), Mouse Cd207 (246278), Rat Cd207 (502852), naked mole-rat Cd207 (101721714), domestic guinea pig Cd207 (100717459), sheep CD207 (101107427), dog CD207 (612679), domestic cat CD207 (101098048), cow CD207 (511000)
UniProtKB ID:
Gene ID:
- Human(50489) Summary: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010]
- Mouse(246278) CD207 antigen
- Rat(502852) CD207 molecule, langerin
- naked mole-rat(101721714) CD207 molecule, langerin
- domestic guinea pig(100717459) CD207 molecule, langerin
- sheep(101107427) CD207 molecule, langerin
- dog(612679) CD207 molecule, langerin
- domestic cat(101098048) CD207 molecule, langerin
- cow(511000) CD207 molecule, langerin
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CD207 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot