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Merck

CCL2

chemokine (C-C motif) ligand 2

Synonyms:
GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF
Species:
UniProtKB ID:
Gene ID:
  • Human(6347) Summary: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008]
  • Mouse(20296) chemokine (C-C motif) ligand 2
  • Rat(24770) chemokine (C-C motif) ligand 2
  • naked mole-rat(101697988) chemokine (C-C motif) ligand 2
  • domestic guinea pig(100135494) chemokine (C-C motif) ligand 2
  • sheep(101120093) chemokine (C-C motif) ligand 2
  • Domestic Rabbit(100009130) chemokine (C-C motif) ligand 2
  • sheep(100294591) chemokine (C-C motif) ligand 2
  • dog(403981) chemokine (C-C motif) ligand 2
  • cow(281043) chemokine (C-C motif) ligand 2
  • Horse(100034136) chemokine (C-C motif) ligand 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CCL2 antibody produced in mouse, clone 2E2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-CCL2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-Monocyte Chemotactic Protein-1 antibody produced in mouse, clone 24822, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
neutralization
western blot

Proteins

Product Number
Description
Species
Monocyte Chemotactic Protein-1 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human
JE/MCP-1 (CCL2) from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
MCP-1/MCAF human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human