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Merck

BAX

BCL2-associated X protein

Synonyms:
BCL2L4
Species:
Human BAX (581), Mouse Bax (12028), Rat Bax (24887), naked mole-rat Bax (101713575), domestic guinea pig Bax (100730890), Goat BAX (100846984), sheep BAX (443059), dog BAX (403523), domestic cat BAX (493837), cow BAX (280730)
UniProtKB ID:
Q07812, A8K4W1, P55269, Q07814, Q07815, Q8WZ49, Q9NR76, Q9NYG7
Gene ID:
  • Human(581) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12028) BCL2-associated X protein
  • Rat(24887) Bcl2-associated X protein
  • naked mole-rat(101713575) BCL2-associated X protein
  • domestic guinea pig(100730890) BCL2-associated X protein
  • Goat(100846984) BCL2-associated X protein
  • sheep(443059) BCL2-associated X protein
  • dog(403523) BCL2-associated X protein
  • domestic cat(493837) BCL2-associated X protein
  • cow(280730) BCL2-associated X protein

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2108447
Anti-BAX, IgG fraction of antiserum,
Species Reactivity
bovine, dog, human, pig
Application
immunohistochemistry
western blot
SAB4504690
Anti-phospho-Bax (pSer184) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
SAB4502546
Anti-BAX antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
SAB4502548
Anti-BAX antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB4502549
Anti-BAX antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry

Proteins

Product Number
Description
Species
SRP5166
BAX, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human