ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
Synonyms:
ATP6B1, RTA1B, VATB, VMA2, VPP3
Species:
Human ATP6V1B1 (525), Mouse Atp6v1b1 (110935), Rat Atp6v1b1 (312488), domestic cat ATP6V1B1 (101098295), cow ATP6V1B1 (338059), Horse ATP6V1B1 (100050282), dog ATP6V1B1 (474628), sheep ATP6V1B1 (101107683), domestic guinea pig Atp6v1b1 (100724011), naked mole-rat Atp6v1b1 (101720999)
UniProtKB ID:
Gene ID:
- Human(525) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq, Jul 2008]
- Mouse(110935) ATPase, H+ transporting, lysosomal V1 subunit B1
- Rat(312488) ATPase, H transporting, lysosomal V1 subunit B1
- domestic cat(101098295) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
- cow(338059) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
- Horse(100050282) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
- dog(474628) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
- sheep(101107683) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
- domestic guinea pig(100724011) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
- naked mole-rat(101720999) ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ATP6V1B1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-ATP6V1B1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot