ARHGAP4
Rho GTPase activating protein 4
Synonyms:
C1, RGC1, RhoGAP4, SrGAP4, p115
Species:
Human ARHGAP4 (393), Mouse Arhgap4 (171207), Rat Arhgap4 (246249), naked mole-rat Arhgap4 (101725190), domestic guinea pig Arhgap4 (100735978), sheep ARHGAP4 (101107503), dog ARHGAP4 (492245), Horse ARHGAP4 (100057993), cow ARHGAP4 (100124430), domestic cat ARHGAP4 (101089250)
UniProtKB ID:
Gene ID:
- Human(393) Summary: This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- Mouse(171207) Rho GTPase activating protein 4
- Rat(246249) Rho GTPase activating protein 4
- naked mole-rat(101725190) Rho GTPase activating protein 4
- domestic guinea pig(100735978) Rho GTPase activating protein 4
- sheep(101107503) Rho GTPase activating protein 4
- dog(492245) Rho GTPase activating protein 4
- Horse(100057993) Rho GTPase activating protein 4
- cow(100124430) Rho GTPase activating protein 4
- domestic cat(101089250) Rho GTPase activating protein 4
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