ALDOB
aldolase B, fructose-bisphosphate
Synonyms:
ALDB, ALDO2
Species:
Human ALDOB (229), Mouse Aldob (230163), Rat Aldob (24190), domestic guinea pig Aldob (100720708), naked mole-rat Aldob (101713582), sheep ALDOB (443440), Domestic Rabbit ALDOB (100328925), Zebrafish aldob (321664), cow ALDOB (515263), Horse ALDOB (100054480) ...More
UniProtKB ID:
Gene ID:
- Human(229) Summary: Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
- Mouse(230163) aldolase B, fructose-bisphosphate
- Rat(24190) aldolase B, fructose-bisphosphate
- domestic guinea pig(100720708) aldolase B, fructose-bisphosphate
- naked mole-rat(101713582) aldolase B, fructose-bisphosphate
- sheep(443440) aldolase B, fructose-bisphosphate
- Domestic Rabbit(100328925) aldolase B, fructose-bisphosphate
- Zebrafish(321664) aldolase b, fructose-bisphosphate
- cow(515263) aldolase B, fructose-bisphosphate
- Horse(100054480) aldolase B, fructose-bisphosphate
- domestic cat(101097025) aldolase B, fructose-bisphosphate
- dog(474787) aldolase B, fructose-bisphosphate
- chicken(427308) aldolase B, fructose-bisphosphate
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ALDOB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Kits
Product Number
Description
Species
Aldolase Activity Colorimetric Assay Kit, Sufficient for 100 Colorimetric tests,
Species
mouse, human, rat