ACTN1
actinin, alpha 1
Synonyms:
BDPLT15
Species:
Human ACTN1 (87), Mouse Actn1 (109711), Rat Actn1 (81634), Zebrafish actn1 (560400), cow ACTN1 (524770), domestic cat ACTN1 (101097986), dog ACTN1 (480369), chicken ACTN1 (373918), domestic guinea pig Actn1 (100721342), naked mole-rat Actn1 (101711839) ...More
UniProtKB ID:
Gene ID:
- Human(87) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(109711) actinin, alpha 1
- Rat(81634) actinin, alpha 1
- Zebrafish(560400) actinin, alpha 1
- cow(524770) actinin, alpha 1
- domestic cat(101097986) actinin, alpha 1
- dog(480369) actinin, alpha 1
- chicken(373918) actinin, alpha 1
- domestic guinea pig(100721342) actinin, alpha 1
- naked mole-rat(101711839) actinin, alpha 1
- sheep(101122194) actinin, alpha 1
- Domestic Rabbit(100341378) actinin, alpha 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-α-Actinin antibody produced in mouse, clone BM-75.2, ascites fluid,
Species Reactivity
bovine, chicken, human, mouse
Application
immunofluorescence
microarray
western blot
microarray
western blot
Proteins
Product Number
Description
Species
α-Actinin from chicken gizzard, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
Species
mouse, chicken, rat, human