SAB4300149

Anti-phospho-HIST1H3D (pSer¹⁰) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-H3/b antibody produced in rabbit, Anti-H3FB antibody produced in rabbit, Anti-histone cluster 1, H3d antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~17 kDa
• species reactivity: rat, human, mouse
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (R-K-SP-T-G)
• NCBI accession no.: NP_003521.2
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer10)
• Gene Information: human ... HIST1H3D(8351)

Descripción

Immunogen

Peptide sequence around phosphorylation site of serine 10 (R-K-S(p)-T-G), according to the protein HIST1H3D.

Features and Benefits

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Target description

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable