Saltar al contenido
MilliporeSigma
Todas las fotos(1)

Key Documents

SAB2500307

Sigma-Aldrich

Anti-DGAT1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-ACAT related gene product 1, Anti-ARGP1, Anti-Acyl coenzyme A:cholesterol acyltransferase related gene 1, Anti-DGAT, Anti-Diacylglycerol O-acyltransferase homolog 1

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, rat, canine, mouse

technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DGAT1(8694)

General description

Diacylglycerol O-acyltransferase 1 (DGAT1) is a 500kDa, hydrophobic protein, which is highly expressed in the skin, mammary gland, adipose tissue, small intestine and testis. The gene encoding it is localized on human chromosome 8q24.3.

Immunogen

Peptide with sequence C-QNSMKPFKDMDYS from the internal region of the protein sequence according to NP_036211.1.

Application

Anti-DGAT1 antibody produced in goat has been used in Western blotting.

Biochem/physiol Actions

Diacylglycerol O-acyltransferase 1 (DGAT1) has a role in the biosynthesis of triglycerides. Mutations in the gene have been linked to congenital diarrhea and protein-losing enteropathy. DGAT1 is also associated with metabolic disorders like diabetes and obesity.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters
Chi-Liang
Journal of Lipid Research (2005)
Iván P Uray et al.
Molecular pharmacology, 81(2), 228-238 (2011-11-05)
Synthetic rexinoids effectively suppress both estrogen receptor-positive and estrogen receptor-negative mammary tumors in animal models, which makes them prime candidates for a novel class of cancer-preventive agents. When used in combination with chemotherapy for non-small-cell lung cancer, the rexinoid bexarotene
Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea.
Gluchowski NL
Journal of Lipid Research (2017)
Prolonged silencing of diacylglycerol acyltransferase-1 induces a dedifferentiated phenotype in human liver cells.
Chang S
Journal of Cellular and Molecular Medicine (2016)
Cancer-Preventive Rexinoid Modulates Neutral Lipid Contents of Mammary Epithelial Cells through a Peroxisome Proliferator-Activated Receptor ?-Dependent Mechanism
Ivan P
Molecular Pharmacology (2012)

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico