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P8247

Sigma-Aldrich

Anti-Potassium Channel KIR3.3 (GIRK3) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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About This Item

MDL number:
MFCD07370455
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat, mouse, human

technique(s)

western blot: 1:200 using rat brain membranes

UniProt accession no.

Q92806

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCNJ9(3765)
mouse ... Kcnj9(16524)
rat ... Kcnj9(116560)

Immunogen

GST fusion protein with sequence corresponding to residues 344-361 of rat KIR3.3 (GIRK3). The sequence is identical in mouse and human.

Physical form

Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin, 5% sucrose, and 0.025% sodium azide.

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Storage Class

10 - Combustible liquids

Certificados de análisis (COA)

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Young-Joo Yi et al.
Systems biology in reproductive medicine, 57(6), 296-308 (2011-11-08)
The GIRK2-containing inward-rectifying K(+) ion channels have been implicated in mammalian spermatogenesis. While the Girk2 null mice are fertile, the male weaver transgenic mice carrying a gain-of-function mutation in the Girk2 gene are infertile. To establish the exact period of
Carlo Corona et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(27), 6102-6113 (2018-06-08)
Activating Transcription Factor 4 (ATF4) has been postulated as a key regulator of learning and memory. We previously reported that specific hippocampal ATF4 downregulation causes deficits in synaptic plasticity and memory and reduction of glutamatergic functionality. Here we extend our
G protein regulation of potassium ion channels.
M Yamada et al.
Pharmacological reviews, 50(4), 723-760 (1998-12-22)
M D Mark et al.
European journal of biochemistry, 267(19), 5830-5836 (2000-09-21)
G-protein regulated inward-rectifier potassium channels (GIRK) are part of a superfamily of inward-rectifier K+ channels which includes seven family members. To date four GIRK subunits, designated GIRK1-4 (also designated Kir3.1-4), have been identified in mammals, and GIRK5 has been found

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