402923

Chloroacetic acid

ACS reagent, ≥99.0%

• Sinónimos: Monochloroacetic acid
• Fórmula lineal: ClCH₂COOH
• Número de CAS: 79-11-8
• Peso molecular: 94.50
• Beilstein/REAXYS Number: 605438
• EC Number: 201-178-4
• MDL number: MFCD00002683
• UNSPSC Code: 12352100
• PubChem Substance ID: 24865140
• NACRES: NA.21

Propiedades

• grade: ACS reagent
• Quality Level: 200
• vapor density: 3.26 (vs air)
• vapor pressure: 0.75 mmHg ( 20 °C)
• assay: ≥99.0%
• form: solid
• impurities: ≤0.01% Carbonyl compounds (as acetone); ≤0.01% Carbonyl compunds (other than acetone); ≤0.01% insolubles
• ign. residue: <0.02%
• bp: 189 °C (lit.)
• mp: 60-63 °C (lit.)

Descripción

General description

Chloroacetic acid (CAA, monochloroacetic acid, MCAA) is a halogenated aliphatic carboxylic acid. Its mutagenic effects have been studied in Rattus norvegicus.[1] The rate of degradation of MCA by photocatalysis using TiO₂ at pH3 is reported to be enhanced under the influence of ozone.[2] CAA is an irritant that hydrolyzes proteins resulting in degradation of the cells. This property has been applied in treating plantar warts.[3]

Application

Chloroacetic acid may be used to synthesize the following:

• Thiocarbamoylthioacetic acid derivatives.[4]
• 4-Thiazolone derivatives.[5]
• Triazinothiazolone derivatives.[6]
• Water soluble carboxymethyl chitosan.[7]

Disclaimer

“The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.”

Información de seguridad

• pictograms: GHS06,GHS05,GHS09
• signalword: Danger
• hcodes: H301 + H311 + H331,H314,H335,H400
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 258.8 °F - closed cup
• flash_point_c: 126 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges