MAB3199Z

Anti-E-Cadherin Antibody, clone 67A4, Azide Free

clone 67A4, Chemicon^®, from mouse

• Sinónimos: CD324, MAB3199
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 67A4, monoclonal
• species reactivity: human
• packaging: antibody small pack of 25 μg
• manufacturer/tradename: Chemicon^®
• technique(s): flow cytometry: suitable; immunofluorescence: suitable
• isotype: IgG1
• NCBI accession no.: NM_004360.2
• UniProt accession no.: P12830
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CDH1(999)

Descripción

Specificity

Antibodies against E-cadherin are suitable to characterize epithelial cells. E-Cadherin is involved in adhesion of epithelial cells (mostly homotypic and homophilic). E-cadherin is also expressed on immature erythroid cells. The antibody 67A4 is suitable to study E cadherin expression by flow cytometry. In addition, it blocks the interaction of E-cadherin molecules and therefore is suitable to study E-cadherin-mediated signal transduction.

Immunogen

T-47D breast carcinoma line.

Application

Anti-E-Cadherin Antibody, clone 67A4, Azide Free is an antibody against E-Cadherin for use in FC & IF.

Immunoblotting

FACS Analysis

Functional blocking of E-cadherin

Does not work well for immunoprecipitation

Optimal working dilutions must be determined by end user.

Quality

Tested

Physical form

Format: Purified

Liquid in 0.02M PBS with NaCl, pH=7.6, with no preservatives. Protein A purified immunoglobulin.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany