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D4379

Sigma-Aldrich

3,3-Dimethylglutaric acid

98%

Sinónimos:

3,3-Dimethylpentanedioic acid, NSC 14987, NSC 49114

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About This Item

Fórmula lineal:
HOOCCH2C(CH3)2CH2COOH
Número de CAS:
4839-46-7
Peso molecular:
160.17
Beilstein/REAXYS Number:
1765439
EC Number:
225-425-0
MDL number:
MFCD00002716
UNSPSC Code:
12352100
PubChem Substance ID:
57654102
NACRES:
NA.22

assay

98%

form

powder

mp

100-102 °C (lit.)

SMILES string

CC(C)(CC(O)=O)CC(O)=O

InChI

1S/C7H12O4/c1-7(2,3-5(8)9)4-6(10)11/h3-4H2,1-2H3,(H,8,9)(H,10,11)

InChI key

DUHQIGLHYXLKAE-UHFFFAOYSA-N

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Application

Reactant involved in:
  • Cyclodehydration of diols
  • Synthesis of conjugates of betulin derivatives used as anti-HIV agents
  • Preparation of dimeric peptide antagonists of IgG-FcRn interaction
  • Microwave-assisted protection of glutaraldehyde
  • Synthesis of glycyrrhetinic acid derivatives for proteasome inhibition
  • Catalytic, asymmetric transannular aldolizations

Quality

May contain trace amounts of toluene.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

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Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 127, 61-67 (2017-05-20)
[
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Journal of biomedical materials research. Part A, 105(5), 1243-1251 (2017-02-09)
A family of pH-responsive terpolymers composed of methacrylic acid (MAA), N-vinyl pyrrolidone (NVP), and poly(ethylene glycol) monomethylether monomethacrylate (PEGMMA) have been developed and evaluated for their pH-responsive swelling behavior, protein-loading capabilities, and cytocompatibility. These terpolymer hydrogels, designated as P((MAA-co-NVP)-g-EG), were
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Journal of drug targeting, 25(9-10), 818-828 (2017-07-22)
'Polymer Enzyme Liposome Therapy' (PELT) is a two-step anticancer approach in which a liposomal drug and polymer-phospholipase conjugate are administered sequentially to target the tumour interstitium by the enhanced permeability and retention effect, and trigger rapid, local, drug release. To
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Walls isolated from cucumber hypocotyls retain autolytic activities and the ability to extend when placed under the appropriate conditions. To test whether autolysis and extension are related, we treated the walls in various ways to enhance or inhibit long-term wall
Rachel Huey et al.
International journal of pharmaceutics, 525(1), 12-20 (2017-04-17)
Drug delivery to the brain is still a major challenge in the field of therapeutics, especially for large and hydrophilic compounds. In order to achieve drug delivery of therapeutic concentration in the central nervous system, the problematic blood brain barrier
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