375772

1-Acetyl-3-indolecarboxaldehyde

98%

• Sinónimos: N-Acetylindol-3-carboxaldehyde, NSC 61289
• Fórmula empírica (notación de Hill): C₁₁H₉NO₂
• Número de CAS: 22948-94-3
• Peso molecular: 187.19
• EC Number: 245-347-0
• MDL number: MFCD00039691
• UNSPSC Code: 12352100
• PubChem Substance ID: 24863403
• NACRES: NA.22

Propiedades

• assay: 98%
• mp: 165 °C (lit.)
• SMILES string: CC(=O)n1cc(C=O)c2ccccc12
• InChI: 1S/C11H9NO2/c1-8(14)12-6-9(7-13)10-4-2-3-5-11(10)12/h2-7H,1H3
• InChI key: LCJLFGSKHBDOAY-UHFFFAOYSA-N

Descripción

General description

1-Acetyl-3-indolecarboxaldehyde participates in the preparation and characterization of three RNA-specific fluorescent probes (E36, E144 and F22), useful in live cell imaging.

Application

1-Acetyl-3-indolecarboxaldehyde may be used to prepare the thiosemicarbazones, via condensation reaction.

Reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture
Reactant for preparation of homoallylic amines as antimicrobial agents
Reactant for preparation of pyrrole-based hydrazones as potential tuberculostatics
Reactant for synthesis of neoechinulin A and derivatives
Reactant for synthesis of substituted (Z)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-one and (Z)-(±)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol derivatives as potent thermal sensitizing agents
Reactant for preparation of RNA-specific live cell imaging probes E36, E144 and F22

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves