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36295

Sigma-Aldrich

2,3-Dichloro-1-propanol

≥97.0% (GC)

Sinónimos:

Glycerol-α,β-dichlorohydrin

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About This Item

Fórmula lineal:
ClCH2CHClCH2OH
Número de CAS:
616-23-9
Peso molecular:
128.99
Beilstein/REAXYS Number:
1732060
EC Number:
210-470-0
MDL number:
MFCD00040446
UNSPSC Code:
12352100
PubChem Substance ID:
57649508
NACRES:
NA.22

assay

≥97.0% (GC)

density

1.360 g/mL at 20 °C (lit.)

SMILES string

OCC(Cl)CCl

InChI

1S/C3H6Cl2O/c4-1-3(5)2-6/h3,6H,1-2H2

InChI key

ZXCYIJGIGSDJQQ-UHFFFAOYSA-N

General description

2,3-Dichloro-1-propanol belongs to the group of chloropropanols. Inhibitory effects of 2,3-dichloro-1-propanol on T cell both in vivo and in vitro is reported. Improved enantioselective resolution of (R,S)-2,3-dichloro-1-propanol to (S)-2, 3-dichloro-1-propanol by whole cells of a recombinant Escherichia coli in n-heptane-aqueous biphasic system is reported.

Application

2,3-Dichloro-1-propanol may be employed as carbon and energy supplement for the growth of Pseudomonas putida strain (MC4).

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

199.4 °F

flash_point_c

93 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Muhammad Irfan Arif et al.
Applied and environmental microbiology, 78(17), 6128-6136 (2012-07-04)
A Pseudomonas putida strain (MC4) that can utilize 2,3-dichloro-1-propanol (DCP) and several aliphatic haloacids and haloalcohols as sole carbon and energy source for growth was isolated from contaminated soil. Degradation of DCP was found to start with oxidation and concomitant
K Fujishiro et al.
Fukuoka igaku zasshi = Hukuoka acta medica, 85(8), 247-250 (1994-08-01)
The toxicity of dichloropropanols (DCPs) was investigated by hematological and blood chemical examination. Solutions of two isomers of DCPs, 1,3-dichloro-2-propanol (DC2P) and 2,3-dichloro-1-propanol (DC1P) were dissolved in saline at a concentration of 100 mg/ml and 0.1 ml of each was
C Aguilar et al.
Journal of chromatography. A, 867(1-2), 207-218 (2000-02-12)
On-line combination of equilibrium sorptive enrichment and gas chromatography is used for the analysis of a group of pollutants varying widely in polarity and volatility in aqueous samples at trace levels. For the ESE process open-tubular traps were used. The
A J Effendi et al.
Applied and environmental microbiology, 66(7), 2882-2887 (2000-07-06)
2,3-Dichloro-1-propanol is more chemically stable than its isomer, 1, 3-dichloro-2-propanol, and is therefore more difficult to degrade. The isolation of bacteria capable of complete mineralization of 2, 3-dichloro-1-propanol was successful only from enrichments at high pH. The bacteria thus isolated
Jing Lu et al.
International immunopharmacology, 17(2), 321-328 (2013-07-16)
2,3-Dichloro-1-propanol (2,3-DCP) is a member of a group of chemicals known as chloropropanols. Currently, immunotoxicity of 2,3-DCP has not been reported. In the present study, we studied its inhibitory effects on T cell both in vivo and in vitro. The
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