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MilliporeSigma

ZYX

zyxin

Sinónimos:
ESP-2, HED-2
Especie:
ID UniProtKB:
ID del gen:
  • Human(7791) Summary: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(22793) zyxin
  • Rat(114636) zyxin
  • fruit fly(317824) Zyxin
  • dog(482736) zyxin
  • domestic cat(101099953) zyxin
  • Zebrafish(564246) zyxin
  • chicken(418300) zyxin
  • cow(768226) zyxin
  • sheep(101123626) zyxin
  • domestic guinea pig(100727523) zyxin
  • naked mole-rat(101710025) zyxin

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ZYX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-Zyxin, serum, from rabbit,
Reactividad de especies
human, monkey, mouse
Aplicación
immunocytochemistry
western blot
Anti-ZYX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Zyxin Antibody, clone 4F9P3, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
immunofluorescence
western blot
Monoclonal Anti-ZYX antibody produced in mouse, clone 2C10-4A7, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunoprecipitation (IP)

western blot

Proteins

Referencia del producto
Descripción
Especie
Monoclonal Anti-ZYX antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2502, purified immunoglobulin, buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Zyx,
Especie
mouse