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Merck

TSLP

thymic stromal lymphopoietin

Sinónimos:
Especie:
Human TSLP (85480), Mouse Tslp (53603), Rat Tslp (688621), domestic cat TSLP (101085857), Horse TSLP (100302635), dog TSLP (607671), domestic guinea pig Tslp (101788673)
ID UniProtKB:
Q969D9, Q8IW99
ID del gen:
  • Human(85480) Summary: This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
  • Mouse(53603) thymic stromal lymphopoietin
  • Rat(688621) thymic stromal lymphopoietin
  • domestic cat(101085857) thymic stromal lymphopoietin
  • Horse(100302635) thymic stromal lymphopoietin
  • dog(607671) thymic stromal lymphopoietin
  • domestic guinea pig(101788673) thymic stromal lymphopoietin

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ELISA

Referencia del producto
Descripción
Especie
RAB0503
Human TSLP ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Especie
human
RAB0504
Mouse TSLP ELISA Kit, for serum, plasma and cell culture supernatant,
Especie
mouse

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ABT330
Anti-TSLP Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
immunohistochemistry
western blot
ABT334
Anti-TSLP receptor Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
ABF113
Anti-TSLP Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
PRS4023
Anti-TSLP (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
PRS4025
Anti-TSLP (ab3) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot

Proteins

Referencia del producto
Descripción
Especie
SRP4896
TSLP human, recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU075571
MISSION® esiRNA, targeting human TSLP,
Especie
human