TLR9
toll-like receptor 9
Sinónimos:
CD289
Especie:
Human TLR9 (54106), Mouse Tlr9 (81897), Rat Tlr9 (338457), Zebrafish tlr9 (403128), domestic cat TLR9 (493839), Horse TLR9 (100009693), dog TLR9 (403502), cow TLR9 (282602), sheep TLR9 (494547), Goat TLR9 (100860819)
ID UniProtKB:
ID del gen:
- Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
- Mouse(81897) toll-like receptor 9
- Rat(338457) toll-like receptor 9
- Zebrafish(403128) toll-like receptor 9
- domestic cat(493839) toll-like receptor 9
- Horse(100009693) toll-like receptor 9
- dog(403502) toll-like receptor 9
- cow(282602) toll-like receptor 9
- sheep(494547) toll-like receptor 9
- Goat(100860819) toll-like receptor 9
- naked mole-rat(101715478) toll-like receptor 9
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Small Molecule - Antagonist
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TLR9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-TLR9 antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
ANTI-TLR9 antibody produced in mouse, clone 2H5, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot
ANTI-TLR9 antibody produced in mouse, clone 2G3, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot
Anti-TLR9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, goat, horse, human, pig, sheep
Aplicación
western blot