PLCG1
phospholipase C, gamma 1
Sinónimos:
NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
Especie:
Human PLCG1 (5335), Mouse Plcg1 (18803), Rat Plcg1 (25738), Zebrafish plcg1 (373867), chicken PLCG1 (419175), domestic cat PLCG1 (101092925), dog PLCG1 (485874), naked mole-rat Plcg1 (101705192), domestic guinea pig Plcg1 (100716986), cow PLCG1 (281987)
ID UniProtKB:
ID del gen:
- Human(5335) Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18803) phospholipase C, gamma 1
- Rat(25738) phospholipase C, gamma 1
- Zebrafish(373867) phospholipase C, gamma 1
- chicken(419175) phospholipase C, gamma 1
- domestic cat(101092925) phospholipase C, gamma 1
- dog(485874) phospholipase C, gamma 1
- naked mole-rat(101705192) phospholipase C, gamma 1
- domestic guinea pig(100716986) phospholipase C, gamma 1
- cow(281987) phospholipase C, gamma 1
- sheep(101103341) phospholipase C, gamma 1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PLCG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Phospho-PLC gamma 1 (PLCG1)-Y783 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anticuerpo anti-PLCγ-1., Upstate®, from mouse,
Reactividad de especies
bovine, human, mouse, rabbit, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Phospho-PLCG1-S1248 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-PLC gamma 1 (PLCG1) Antibody, clone 6V9U10, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot