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PAK4

p21 protein (Cdc42/Rac)-activated kinase 4

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(10298) Summary: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(70584) p21 protein (Cdc42/Rac)-activated kinase 4
  • Rat(292756) p21 protein (Cdc42/Rac)-activated kinase 4
  • domestic guinea pig(100736193) p21 protein (Cdc42/Rac)-activated kinase 4
  • naked mole-rat(101720492) p21 protein (Cdc42/Rac)-activated kinase 4
  • Domestic Rabbit(100341934) p21 protein (Cdc42/Rac)-activated kinase 4
  • sheep(101115152) p21 protein (Cdc42/Rac)-activated kinase 4
  • Zebrafish(431769) p21 protein (Cdc42/Rac)-activated kinase 4
  • chicken(770462) p21 protein (Cdc42/Rac)-activated kinase 4
  • cow(539742) p21 protein (Cdc42/Rac)-activated kinase 4
  • Horse(100067000) p21 protein (Cdc42/Rac)-activated kinase 4
  • domestic cat(101098348) p21 protein (Cdc42/Rac)-activated kinase 4
  • dog(484513) p21 protein (Cdc42/Rac)-activated kinase 4

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PAK4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-PAK4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-PAK4 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
Anti-phospho-PAK4/5/6 (pSer474) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
Monoclonal Anti-PAK4 antibody produced in mouse, clone 3F10, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot

Proteins

Referencia del producto
Descripción
Especie
PAK4 Protein, active, 10 µg, Active, N-terminal His6 & N-terminal GST-tagged, recombinant, human PAK4 amino acids 295-end, for use in Kinase Assays.,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Pak4,
Especie
mouse
MISSION® esiRNA, targeting human PAK4,
Especie
human