MMP14
matrix metallopeptidase 14 (membrane-inserted)
Sinónimos:
MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1
Especie:
Human MMP14 (4323), Mouse Mmp14 (17387), Rat Mmp14 (81707), chicken MMP14 (426253), cow MMP14 (281915), Horse MMP14 (100034170), domestic cat MMP14 (101089776), dog MMP14 (403823), naked mole-rat Mmp14 (101723795), Domestic Rabbit MMP14 (100009598) ...Más
ID UniProtKB:
ID del gen:
- Human(4323) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
- Mouse(17387) matrix metallopeptidase 14 (membrane-inserted)
- Rat(81707) matrix metallopeptidase 14 (membrane-inserted)
- chicken(426253) matrix metallopeptidase 14 (membrane-inserted)
- cow(281915) matrix metallopeptidase 14 (membrane-inserted)
- Horse(100034170) matrix metallopeptidase 14 (membrane-inserted)
- domestic cat(101089776) matrix metallopeptidase 14 (membrane-inserted)
- dog(403823) matrix metallopeptidase 14 (membrane-inserted)
- naked mole-rat(101723795) matrix metallopeptidase 14 (membrane-inserted)
- Domestic Rabbit(100009598) matrix metallopeptidase 14 (membrane-inserted)
- domestic guinea pig(100732039) matrix metallopeptidase 14 (membrane-inserted)
- sheep(443116) matrix metallopeptidase 14 (membrane-inserted)
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Antibodies
Product Number
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-MMP-14, dominio catalítico, clon LEM-2/15.8, clone LEM-2/15.8, Chemicon®, from mouse,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-MMP-14 Antibody, serum, Chemicon®,
Reactividad de especies
human
Aplicación
ELISA
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
western blot
Anti-Human MT1-MMP catalytic domain Antibody, clone 3G4.2, clone 3G4.2, Chemicon®, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MT1-MMP Antibody, hinge region, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-MMP-14 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Descripción
Especie
MMP-14, human, prodomain, catalytic domain, and hemopexin domain, E. coli recombinant, ,
Especie
human