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Merck

ITGAV

integrin, alpha V

Sinónimos:
CD51, MSK8, VNRA, VTNR
Especie:
Human ITGAV (3685), Mouse Itgav (16410), Rat Itgav (296456), sheep ITGAV (443143), Domestic Rabbit ITGAV (100008956), domestic guinea pig Itgav (100728575), naked mole-rat Itgav (101717672), Zebrafish itgav (100151255), cow ITGAV (281875), Horse ITGAV (100068706) ...Más
ID UniProtKB:
P06756, A0AV67, B0LPF4, B7Z883, D3DPG8, E7EWZ6, Q53SK4, Q59EB7
ID del gen:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • sheep(443143) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • Horse(100068706) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • dog(488437) integrin, alpha V
  • chicken(396420) integrin, alpha V

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Small Molecule - Antagonist

Product Number
Descripción
Especie
G1269
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Especie
human

Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
MAB2077Z
Anticuerpo anti-integrina αVβ6, clon 10D5, sin azida, clone 10D5, Chemicon®, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
flow cytometry
immunoprecipitation (IP)
MAB1976
Anticuerpo anti-integrina αVβ3, clon LM609, clone LM609, Chemicon®, from mouse,
Reactividad de especies
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Aplicación
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
MAB1978-I
Anti-Integrin αV Antibody, clone LM142, ,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence
immunohistochemistry
neutralization
MAB1978
Anti-Integrin αV Antibody, clone LM142, ascites fluid, clone LM142, Chemicon®,
Reactividad de especies
human
Aplicación
immunohistochemistry
immunoprecipitation (IP)
MAB1976Z
Anti-Integrin αVβ3 Antibody, clone LM609, Azide Free, clone LM609, Chemicon®, from mouse,
Reactividad de especies
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Aplicación
flow cytometry
immunohistochemistry
immunoprecipitation (IP)

Proteins

Product Number
Descripción
Especie
CC102A
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Especie
human
CC101
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
Especie
human

esiRNA

Product Number
Descripción
Especie
EMU051281
MISSION® esiRNA, targeting mouse Itgav,
Especie
mouse
EHU002301
MISSION® esiRNA, targeting human ITGAV,
Especie
human