GRM1
glutamate receptor, metabotropic 1
Sinónimos:
GPRC1A, MGLU1, MGLUR1, SCAR13
Especie:
Human GRM1 (2911), Mouse Grm1 (14816), Rat Grm1 (24414), domestic guinea pig Grm1 (100730891), naked mole-rat Grm1 (101712477), Domestic Rabbit GRM1 (100356201), Zebrafish grm1 (100150246), dog GRM1 (484024), domestic cat GRM1 (101094104), cow GRM1 (540485) ...Más
ID UniProtKB:
ID del gen:
- Human(2911) Summary: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Mouse(14816) glutamate receptor, metabotropic 1
- Rat(24414) glutamate receptor, metabotropic 1
- domestic guinea pig(100730891) glutamate receptor, metabotropic 1
- naked mole-rat(101712477) glutamate receptor, metabotropic 1
- Domestic Rabbit(100356201) glutamate receptor, metabotropic 1
- Zebrafish(100150246) glutamate receptor, metabotropic 1
- dog(484024) glutamate receptor, metabotropic 1
- domestic cat(101094104) glutamate receptor, metabotropic 1
- cow(540485) glutamate receptor, metabotropic 1
- Horse(100060603) glutamate receptor, metabotropic 1
- chicken(421614) glutamate receptor, metabotropic 1
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Small Molecule - Agonist
Referencia del producto
Descripción
Especie
Small Molecule - Antagonist
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-Glutamate antibody produced in mouse, clone GLU-4, ascites fluid,
Reactividad de especies
wide range
Aplicación
ELISA
Anti-GRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Metabotropic Glutamate Receptor 1α Antibody, pain, CT, Chemicon®, from rabbit,
Reactividad de especies
human, monkey, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Metabotropic Glutamate Receptor 1 Antibody, Chemicon®, from rabbit,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-mGluR1 Antibody, Upstate®, from rabbit,
Reactividad de especies
rat
Aplicación
western blot
Small Molecule - Inhibitor
Referencia del producto
Descripción
Especie
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Especie
rat, human
Small Molecule - Mixed Agonist/Antagonist
Referencia del producto
Descripción
Especie
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Especie
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Especie
rat, human