GNRHR
gonadotropin-releasing hormone receptor
Sinónimos:
GNRHR1, GRHR, HH7, LHRHR, LRHR
Especie:
Human GNRHR (2798), Mouse Gnrhr (14715), Rat Gnrhr (81668), chicken GNRHR (427517), dog GNRHR (403718), cow GNRHR (281798), domestic cat GNRHR (101088838), Horse GNRHR (100033874), domestic guinea pig Gnrhr (100135532), naked mole-rat Gnrhr (101704341)
ID UniProtKB:
ID del gen:
- Human(2798) Summary: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14715) gonadotropin releasing hormone receptor
- Rat(81668) gonadotropin releasing hormone receptor
- chicken(427517) gonadotropin-releasing hormone receptor
- dog(403718) gonadotropin-releasing hormone receptor
- cow(281798) gonadotropin-releasing hormone receptor
- domestic cat(101088838) gonadotropin-releasing hormone receptor
- Horse(100033874) gonadotropin-releasing hormone receptor
- domestic guinea pig(100135532) gonadotropin releasing hormone receptor
- naked mole-rat(101704341) gonadotropin-releasing hormone receptor
- Domestic Rabbit(100009509) gonadotropin-releasing hormone receptor
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Small Molecule - Agonist
Referencia del producto
Descripción
Especie
Goserelin for NMR identification, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Small Molecule - Antagonist
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GRHR/LRHR antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
canine, human
Aplicación
ELISA
western blot
western blot
Anti-GnRH-R Antibody, clone F1G4, clone FIG4, from mouse,
Reactividad de especies
human
Aplicación
ELISA
dot blot
flow cytometry
immunohistochemistry
western blot
dot blot
flow cytometry
immunohistochemistry
western blot
Anti-GNRHR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-GNRHR antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunofluorescence
immunofluorescence
Proteins
Referencia del producto
Descripción
Especie
[des-Gly10, D-Ala6]-LH-RH etilamida acetate salt hydrate, ≥97% (HPLC), powder,
Especie
mouse, human
esiRNA
Referencia del producto
Descripción
Especie
