CLDN18
claudin 18
Sinónimos:
SFTA5, SFTPJ
Especie:
Human CLDN18 (51208), Mouse Cldn18 (56492), Rat Cldn18 (315953), chicken CLDN18 (429135), domestic cat CLDN18 (101093797), cow CLDN18 (511460), dog CLDN18 (477079), sheep CLDN18 (101112106), domestic guinea pig Cldn18 (100730947), naked mole-rat Cldn18 (101705422)
ID UniProtKB:
ID del gen:
- Human(51208) Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
- Mouse(56492) claudin 18
- Rat(315953) claudin 18
- chicken(429135) claudin 18
- domestic cat(101093797) claudin 18
- cow(511460) claudin 18
- dog(477079) claudin 18
- sheep(101112106) claudin 18
- domestic guinea pig(100730947) claudin 18
- naked mole-rat(101705422) claudin 18
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Antibodies
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Aplicación
Anti-CLDN18 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-CLDN18 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, human, mouse, pig, rabbit, rat
Aplicación
western blot
Anti-CLDN18, affinity isolated antibody,
Reactividad de especies
horse, human, mouse, rat
Aplicación
western blot
esiRNA
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