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ANPEP

alanyl (membrane) aminopeptidase

Sinónimos:
APN, CD13, GP150, LAP1, P150, PEPN
Especie:
ID UniProtKB:
ID del gen:
  • Human(290) Summary: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
  • Mouse(16790) alanyl (membrane) aminopeptidase
  • Rat(81641) alanyl (membrane) aminopeptidase
  • chicken(395667) alanyl (membrane) aminopeptidase
  • domestic cat(493785) alanyl (membrane) aminopeptidase
  • Horse(100050397) alanyl (membrane) aminopeptidase
  • cow(404191) alanyl (membrane) aminopeptidase
  • dog(403913) alanyl (membrane) aminopeptidase
  • sheep(101104860) alanyl (membrane) aminopeptidase
  • Domestic Rabbit(100009167) alanyl (membrane) aminopeptidase
  • domestic guinea pig(100727522) alanyl (membrane) aminopeptidase
  • naked mole-rat(101706035) alanyl (membrane) aminopeptidase

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ELISA

Referencia del producto
Descripción
Especie
Human Aminopeptidase N ELISA, for serum, plasma and cell culture supernatants,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ANPEP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Milli-Mark® Anti-CD13-FITC Antibody, clone WM-47, clone WM-47, Milli-Mark®, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
CD13 (SP187) Rabbit Monoclonal Antibody, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
CD13 (EP117) Rabbit Monoclonal Primary Antibody, ,
Reactividad de especies
Aplicación
immunohistochemistry
Anti-CD13 antibody, Rabbit monoclonal, clone SP182, recombinant, expressed in proprietary host, affinity isolated antibody,
Reactividad de especies
human, pig, rabbit
Aplicación
flow cytometry
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Actinonin, ,
Especie
human
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine, 97%,
Especie
human, mouse, rat
Flavone, ≥99.0%,
Especie
human, rat, mouse

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ANPEP,
Especie
human
MISSION® esiRNA, targeting mouse Anpep,
Especie
mouse