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Enhanced sensitive love wave surface acoustic wave sensor designed for immunoassay formats.

Sensors (Basel, Switzerland) (2015-05-08)
Mihaela Puiu, Ana-Maria Gurban, Lucian Rotariu, Simona Brajnicov, Cristian Viespe, Camelia Bala
ABSTRACT

We report a Love wave surface acoustic wave (LW-SAW) immunosensor designed for the detection of high molecular weight targets in liquid samples, amenable also for low molecular targets in surface competition assays. We implemented a label-free interaction protocol similar to other surface plasmon resonance bioassays having the advantage of requiring reduced time analysis. The fabricated LW-SAW sensor supports the detection of the target in the nanomolar range, and can be ultimately incorporated in portable devices, suitable for point-of-care testing (POCT) applications.

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