Antimicrobial effects of silver nanoparticles.

Nanomedicine : nanotechnology, biology, and medicine (2007-03-24)
Jun Sung Kim, Eunye Kuk, Kyeong Nam Yu, Jong-Ho Kim, Sung Jin Park, Hu Jang Lee, So Hyun Kim, Young Kyung Park, Yong Ho Park, Cheol-Yong Hwang, Yong-Kwon Kim, Yoon-Sik Lee, Dae Hong Jeong, Myung-Haing Cho
ABSTRACT

The antimicrobial effects of silver (Ag) ion or salts are well known, but the effects of Ag nanoparticles on microorganisms and antimicrobial mechanism have not been revealed clearly. Stable Ag nanoparticles were prepared and their shape and size distribution characterized by particle characterizer and transmission electron microscopic study. The antimicrobial activity of Ag nanoparticles was investigated against yeast, Escherichia coli, and Staphylococcus aureus. In these tests, Muller Hinton agar plates were used and Ag nanoparticles of various concentrations were supplemented in liquid systems. As results, yeast and E. coli were inhibited at the low concentration of Ag nanoparticles, whereas the growth-inhibitory effects on S. aureus were mild. The free-radical generation effect of Ag nanoparticles on microbial growth inhibition was investigated by electron spin resonance spectroscopy. These results suggest that Ag nanoparticles can be used as effective growth inhibitors in various microorganisms, making them applicable to diverse medical devices and antimicrobial control systems.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Silver nanospheres, 10 nm avg. part. size, PVP functionalized, 0.02 mg/mL in water
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Silver nanoplates, resonant wavelength, 550 nm, ~1 mg/mL (in water with 5 mM sodium borate buffer), PVP functionalized
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Silver nanospheres, 40 nm avg. part. size, 1 mg/mL (aqueous sodium citrate), citrate functionalized, λmax, 415 nm
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Silver nanospheres, 60 nm avg. part. size, 1 mg/mL in water, PVP functionalized
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Silver nanospheres, 40 nm avg. part. size, 1 mg/mL in water, PVP functionalized
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Silver nanospheres, 200 nm avg. part. size, 0.02 mg/mL (in 2mM aqueous sodium citrate), citrate functionalized
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Silver nanospheres, 80 nm avg. part. size, 0.02 mg/mL (in 2mM aqueous sodium citrate), citrate functionalized
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Silver nanospheres, 30 nm avg. part. size, 0.02 mg/mL (in 2mM aqueous sodium citrate), citrate functionalized
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Silver nanospheres, 60 nm (APS), 1.10 mg/mL in water, BPEI functionalized
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Silver nanospheres, 40 nm avg. part. size, 1 mg/mL in water, PEG functionalized
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Silver nanospheres, 100 nm avg. part. size, 0.02 mg/mL in water, BPEI functionalized
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Silver nanospheres, 80 nm avg. part. size, 0.02 mg/mL in water, PEG functionalized
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Silver nanospheres, 60 nm avg. part. size, 1 mg/mL in water, PEG functionalized
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Silver nanospheres, 60 nm avg. part. size, 0.02 mg/mL in water, PEG functionalized
Sigma-Aldrich
Silver nanospheres, 30 nm avg. part. size, 1 mg/mL (aqueous sodium citrate), citrate functionalized
Sigma-Aldrich
Silver nanospheres, 60 nm avg. part. size, 1 mg/mL (aqueous sodium citrate), citrate functionalized
Sigma-Aldrich
Silver nanospheres, 80 nm avg. part. size, 1 mg/mL (aqueous sodium citrate), citrate functionalized
Sigma-Aldrich
Silver nanospheres, 100 nm avg. part. size, 1 mg/mL (aqueous sodium citrate), citrate functionalized
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Sigma-Aldrich
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