MilliporeSigma
  • Home
  • Search Results
  • Clinico-epidemiological profile of seven adults with spotted fever from a tertiary care hospital in South India.

Clinico-epidemiological profile of seven adults with spotted fever from a tertiary care hospital in South India.

Tropical doctor (2013-12-18)
Kango Gopal Gopinath, Anugrah Chrispal, Harikishan Boorugu, Sara Chandy, John Jude Prakash, Asha Mary Abraham, O C Abraham, Kurien Thomas
ABSTRACT

Spotted fever (SF), a tick-borne rickettsial infection, is being increasingly reported from mainly northern Indian states. A lack of awareness and confirmatory laboratory tests underestimate the incidence of this infection which, in India, is predominantly seen during the rainy season. Many patients diagnosed with viral exanthematous illnesses may be suffering from SF, which is treatable if detected early. There is very little data on SF in adults in southern India. We present seven patients with SF treated between January 2007 and January 2008 in a tertiary care hospital in South India. All presented during the rainy season, with rash (100%) and generalized oedema (71%) being the most common features. There was one death due to type I respiratory failure. Renal failure, shock, aseptic meningitis and hepatitis were other significant abnormalities detected in these patients. Clinicians need to be aware of SF and suspect it in appropriate patients.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Doxycycline monohydrate
Supelco
Doxycycline hyclate, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Doxycycline hyclate, VETRANAL®, analytical standard
Sigma-Aldrich
Doxycycline hyclate
Doxycycline hyclate, European Pharmacopoeia (EP) Reference Standard
USP
Doxycycline hyclate, United States Pharmacopeia (USP) Reference Standard