MilliporeSigma

An efficient new cannabinoid antiemetic in pediatric oncology.

Life sciences (1995-01-01)
A Abrahamov, A Abrahamov, R Mechoulam
ABSTRACT

Delta-8-tetrahydrocannabinol (delta-8-THC), a cannabinoid with lower psychotropic potency than the main Cannabis constituent, delta-9-tetrahydrocannabinol (delta-9-THC), was administered (18 mg/m2 in edible oil, p.o.) to eight children, aged 3-13 years with various hematologic cancers, treated with different antineoplastic drugs for up to 8 months. The total number of treatments with delta-8-THC so far is 480. The THC treatment started two hours before each antineoplastic treatment and was continued every 6 hrs for 24 hours. Vomiting was completely prevented. The side effects observed were negligible.

MATERIALS
Product Number
Brand
Product Description

Supelco
(−)-Δ8-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®