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Phenyl salicylates - a new group of potential antituberculotics.

Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti (2013-02-08)
Karel Waisser, Eva Novotná, Jiří Kuneš, Jiřina Solaříková
ABSTRACT

Antimycobacterial activity of phenyl salicylates (salols) was studied in connection with antituberculotic activity of salicylic derivatives. Phenyl salicylates are esters. Our attention was previously oriented on amides. Phenyl salicylates (salols) represent a new group of antimycobacterial compounds. They are less active than the corresponding amides. The most active compound in the group under study is substituted on phenyl in the salicyl moiety with a 4-methoxy group. The study reports a new item of information about antimycobacterial salicylic derivatives.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Phenyl salicylate, ReagentPlus®, 99%
Sigma-Aldrich
Phenyl salicylate, ≥99%, FG
Supelco
Phenyl salicylate melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Mettler-Toledo Calibration substance ME 30034252, Phenyl salicylate, traceable to primary standards