MilliporeSigma

Dermatitis from phenyl salicylate in safety spectacle frames.

Contact dermatitis (1986-05-01)
T S Sonnex, R J Rycroft
ABSTRACT

We report 3 cases of allergic contact dermatitis behind the ears from wearing the same brand of industrial safety spectacles. In each case, a positive patch test was obtained with scrapings of the plastic frame. In 2 cases further patch tests with constituents of the plastic were carried out; positive patch tests were obtained with phenyl salicylate. Phenyl salicylate is used as an ultraviolet inhibitor in some cellulose acetate butyrate and cellulose acetate propionate formulae. It has previously been reported as a contact sensitizer from its use as a sun screen in a lip salve. Positive patch test reactions were also obtained variously in these patients with balsam of Peru, resorcinol monobenzoate, and epoxy resin.

MATERIALS
Product Number
Brand
Product Description

Supelco
Mettler-Toledo Calibration substance ME 30034252, Phenyl salicylate, traceable to primary standards
Supelco
Phenyl salicylate melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Phenyl salicylate, ≥99%, FG
Sigma-Aldrich
Phenyl salicylate, ReagentPlus®, 99%