We present the case of a 47-year-old man who presented to the Emergency Department (ED) with complaint of left-sided neck pain. He was thought to have a musculoskeletal sprain on his initial visit. However, he returned the following evening with worsening symptoms. On further investigation, he was found to have a non-traumatic retropharyngeal abscess (RPA), a rare infection in the adult patient population. This infection has been studied primarily in the pediatric population, and extrapolation of their studies demonstrates the importance of airway stabilization, antibiotic use targeting polymicrobial organisms, and conservative medical management vs. surgical drainage. We aim to summarize this case and review the literature on retropharyngeal abscess. This patient presented to the ED with complaints of left-sided neck pain. There was no history of trauma or injury to the affected area. He was evaluated and discharged but returned with a deteriorating clinical picture. On further evaluation, he was found to have a non-traumatic RPA. He was admitted to the Otolaryngology service and managed conservatively with intravenous (IV) antibiotics. His condition resolved and he was subsequently discharged from the hospital. The majority of data on diagnosis and treatment of adult RPA have come from the pediatric population. However, the same essential treatment principles apply: airway stabilization, resuscitation, initiation of IV antibiotics, and consultation with an otolaryngology specialist.