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Direct patterning of silanized-biomolecules on semiconductor surfaces.

Langmuir : the ACS journal of surfaces and colloids (2010-11-05)
Dorjderem Nyamjav, Richard C Holz
ABSTRACT

A novel approach to pattern silanized-biomolecules directly onto glass (SiO(x)) substrates via Dip-Pen nanolithography (DPN) and microcontact printing (μCP) is presented. Subsequent hybridization reactions of DPN patterned silanized-DNA with its complementary strands provide "proof-of-concept" that the patterned oligonucleotides maintain their biological activities. The fabrication strategy does not require premodification of substrates and offers a cheap and robust way to immobilize molecules on electronically important semiconductor surfaces.

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(3-Mercaptopropyl)trimethoxysilane, 95%