MilliporeSigma
  • Home
  • Search Results
  • Steroidal saponins from the aerial parts of Cordyline fruticosa L. var. strawberries.

Steroidal saponins from the aerial parts of Cordyline fruticosa L. var. strawberries.

Fitoterapia (2019-03-27)
Beaudelaire K Ponou, Rémy B Teponno, Azefack L Tapondjou, Marie-Aleth Lacaille-Dubois, Luana Quassinti, Massimo Bramucci, Luciano Barboni
ABSTRACT

A new sulfated steroidal derivative (fruticogenin A: 1-sulfo-australigenin-3-sodium sulphate, 1) and three new steroidal saponins named fruticoside K (3-sulfo-spirostan-25(27)-ene-1β,3β-diol-1-O-[α-L-rhamnopyranosyl-(1 → 4)-β-D-fucopyranoside], 2), fruticoside L (3-sulfo-spirostan-25(27)-ene-1β,3β,6α-triol-1-O-[α-L-rhamnopyranosyl-(1 → 4)-β-D-fucopyranoside], 3) and fruticoside M (spirostan-25(27)-ene-1β,3α-diol-1-O-[α-L-rhamnopyranosyl-(1 → 2)-α-L-rhamnopyranoside], 4) were isolated from the aerial parts of Cordyline fruticosa L. var. strawberries. Their structures were established on the basis of 1D and 2D NMR data, mass spectrometry and chemical methods. Compounds 2 and 4 exhibited weak cytotoxicity against melanoma (A375), breast adenocarcinoma (MDA-MB-231), and colon carcinoma (HCT116) human tumor cell lines.