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Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products.

International journal of environmental research and public health (2018-04-14)
Minjin Lee, Joo-Hyon Kim, Daeyeop Lee, Jaewoo Kim, Hyunwoo Lim, Jungkwan Seo, Young-Kwon Park
ABSTRACT

The inhalation of a water aerosol from a humidifier containing disinfectants has led to serious lung injuries in Korea. To promote the safe use of products, the Korean government enacted regulations on the chemicals in various consumer products that could have adverse health effects. Given the concern over the potential health risks associated with the hazardous ingredients in deodorizing consumer products, 17 ingredients were analyzed and assessed according to their health risk on 3 groups by the application type in 47 deodorizing products. The risk assessment study followed a stepwise procedure (e.g., collecting toxicological information, hazard identification/exposure assessment, and screening and detailed assessment for inhalation and dermal routes). The worst-case scenario and maximum concentration determined by the product purpose and application type were used as the screening assessment. In a detailed assessment, the 75th exposure factor values were used to estimate the assumed reasonable exposure to ingredients. The exposed concentrations of seven ingredients were calculated. Due to limitation of toxicity information, butylated hydroxyl toluene for a consumer’s exposure via the dermal route only was conducted for a detailed assessment. This study showed that the assessed ingredients have no health risks at their maximum concentrations in deodorizing products. This approach can be used to establish guidelines for ingredients that may pose inhalation and dermal hazards.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Dess-Martin periodinane, 97%
Sigma-Aldrich
Benzyl butyl phthalate, 98%
Sigma-Aldrich
Diisobutyl phthalate, 99%
Sigma-Aldrich
1,4-Dichlorobenzene, ≥99%
Sigma-Aldrich
Diethyl pyrocarbonate, 96% (NT)