Richard J Flannery et al.
American journal of physiology. Renal physiology, 309(8), F697-F707 (2015-08-21)
Defects in primary cilia lead to a variety of human diseases. One of these, polycystic kidney disease, can be caused by defects in a Ca²⁺-gated ion channel (TRPP2) found on the cilium. Other ciliary functions also contribute to cystogenesis, and